Lack of CaBP1/Caldendrin or CaBP2 Leads to Altered Ganglion Cell Responses

Lack of CaBP1/Caldendrin or CaBP2 Leads to Altered Ganglion Cell Responses

Calcium-binding proteins (CaBPs) form a subfamily of calmodulin-like proteins that were cloned from the retina. CaBP4 and CaBP5 have been shown to be important for normal visual function. Although CaBP1/caldendrin and CaBP2 have been shown to modulate various targets in vitro, it is not known whether they contribute to the transmission of light responses through the retina. Therefore, we genera...

Macaque ganglion cell responses to probe stimuli on modulated backgrounds.

In the natural environment, visual targets have to be detected and identified on changing backgrounds. Here, responses of parasol (magnocellular) ganglion cells to probes on modulated backgrounds are described. At low frequency, the adaptation level of the background influences the probe response, but with increasing frequency there is a strong interaction with the response to the background pe...

Chronic Partial Sleep Deprivation Leads to Altered Serotonergic and Corticotropin Releasing Hormone Regulation of Stress Responses

Frequently disrupted and restricted sleep is a widespread problem in our modern around-theclock society. In the long run, insufficient sleep may have serious repercussions for health and well-being. Indeed, sleep complaints and restricted sleep have been identified as risk factors for various diseases including, for example, mood disorders such as depression. One pathway along which restricted ...

MusaWRKY71 Overexpression in Banana Plants Leads to Altered Abiotic and Biotic Stress Responses

WRKY transcription factors are specifically involved in the transcriptional reprogramming following incidence of abiotic or biotic stress on plants. We have previously documented a novel WRKY gene from banana, MusaWRKY71, which was inducible in response to a wide array of abiotic or biotic stress stimuli. The present work details the effects of MusaWRKY71 overexpression in transgenic banana pla...

Priming Leads to Poor Generation of Central Lack of ICAM-1 on APCs during T Cell